We use tmux at CodePen. It’s essentially so we can all run a single terminal command and it’ll run all the scripts and whathaveyou to fire up our dev environment. Then we have a UI for all the different services and whatnot we run. We can and do update it regularly to help us do our jobs.

I wouldn’t say I love it. The designer part of me wishes I could design something that does what it does with some more appealing pixels. But whatever, it’s a decent system for scripting and automating all our stuff.
To change panels in there, you can literally click on them. That’s usually how I roll because I’m a mouse-loving freak. But one day it stopped working and I couldn’t figure out why. Turns out this checkbox in iTerm got unchecked.

So yeah if it happens to you it’s probably that.
Thanks so much, this is exactly what caused mouse click not working in tmux for me.